Post doc in structural microbiology
Are you interested in working on how bacteria survive nutritional stress by breaking down chemically stable compounds and do you have experience wi
Are you interested in working on how bacteria survive nutritional stress by breaking down chemically stable compounds and do you have experience with single-particle cryo-electron microscopy? Then the Department of Molecular Biology and Genetics invites you to apply for a 2.5-year post doc position.
Expected start date and duration of employment
This is a 30-month position available from August 15th or as soon as possible thereafter.
The position is in the Ditlev E. Brodersen lab, who focus on understanding bacterial defence mechanisms and survival. Carbon-phosphorus lyase is a large enzyme complex required for survival during phosphate starvation by allowing breakdown of stable phosphonate compounds. The successful candidate will join an ambitious team working on deciphering the inner workings of this enzyme complex, including substrate binding and conformational changes that take place during the phosphonate breakdown process with the aim of understanding how some bacteria can break down herbicides and antibiotics. The project requires experience with protein complex purification and structure determination by single particle cryo-EM.
We are looking for a highly skilled and motivated person with a Ph.D. degree in biochemistry, structural biology, or molecular microbiology with an interest in working on deciphering the mechanism of bacterial carbon-phosphorus lyase using biochemistry and structural methods.
The candidate must have:
- Experience with structure determination by single-particle cryo-electron microscopy.
- Experience with protein purification, ideally of large complexes and trapping of reaction intermediates.
A successful candidate has
- A relevant Ph.D. degree and a solid and documented background in structural biology and biochemistry.
- Experience with purification/biochemistry under anaerobic conditions is an advantage.
- Experience with microbiology is an advantage.
- Experience with organic chemistry is an advantage.
Finally, applicants should
- be ambitious and open-minded.
- show strong collaborative skills.
- be able to take initiative and responsibility within a research group.
Who we are
Situated in a newly renovated laboratory complex within the University City, The Department of Molecular Biology and Genetics comprises a vibrant research and education environment. The department currently has 75 full time scientific staff, 95 PhD students and a yearly uptake of around 160 students housed in the same building ensuring a lively setting.
The department has access to state-of-the-art core facilities, including bioimaging, cryo-EM and biophysics cores.
Please refer to http://mbg.au.dk/ for further information about The Department of Molecular Biology and Genetics and to https://nat.au.dk/ and http://www.au.dk/ for information on Faculty of Natural Sciences and Aarhus University, respectively.
The city of Aarhus
In Aarhus you have easy access to beautiful nature, an exciting culture and city life as well as a safe environment for children - a great place for the whole family. The city of Aarhus has everything you need within a surprisingly small area: Exciting national and international jobs, delightful residential areas, a rich cultural life, and beautiful surrounding landscape of woods and coastline that make Aarhus a wonderful place to live and work. See “life in Denmark” at Aarhus and surroundings (au.dk) for further details on the city and the university.
What we offer
The department/centre offers:
- a well-developed research infrastructure, laboratories and access to shared equipment
- an exciting interdisciplinary environment with many national, international and industrial collaborators
- a research climate encouraging lively, open and critical discussion within and across different fields of research
- a work environment with close working relationships, networking and social activities
- a workplace characterised by professionalism, equality, and a healthy work-life balance.
Place of work and area of employment
The place of work is Universitetsbyen 81, 8000 Aarhus C, and the area of employment is Aarhus University with related departments.
For further information, please contact Professor Ditlev Brodersen (firstname.lastname@example.org).
Applications must be received no later than June 27th 2022.
Shortlisting is used. This means that after the deadline for applications – and with the assistance from the assessment committee chairman, and the appointment committee if necessary, – the head of department selects the candidates to be evaluated. All applicants will be notified whether or not their applications have been sent to an expert assessment committee for evaluation. The selected applicants will be informed about the composition of the committee, and each applicant is given the opportunity to comment on the part of the assessment that concerns him/her self. Once the recruitment process is completed a final letter of rejection is sent to the deselected applicants.
Letter of reference
If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline. Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.
Formalities and salary range
Natural Sciences refers to the Ministerial Order on the Appointment of Academic Staff at Danish Universities under the Danish Ministry of Science, Technology and Innovation.
The application must be in English and include a curriculum vitae, degree certificate, a complete list of publications, a statement of future research plans and information about research activities, teaching portfolio and verified information on previous teaching experience (if any). Guidelines for applicants can be found here.
Appointment shall be in accordance with the collective labour agreement between the Danish Ministry of Finance and the Danish Confederation of Professional Associations. Further information on qualification requirements and job content may be found in the Memorandum on Job Structure for Academic Staff at Danish Universities.
Salary depends on seniority as agreed between the Danish Ministry of Finance and the Confederation of Professional Associations.
Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.
Research activities will be evaluated in relation to actual research time. Thus, we encourage applicants to specify periods of leave without research activities, in order to be able to subtract these periods from the span of the scientific career during the evaluation of scientific productivity.
Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Read more here. Please find more information about entering and working in Denmark here.
Aarhus University also offers a Junior Researcher Development Programme targeted at career development for postdocs at AU. You can read more about it here.
The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 38,000 students (FTEs) and 8,000 employees, and has an annual revenues of EUR 885 million. Learn more at www.international.au.dk/
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