Chief Bioinformatics Officer for Danish National Genome Center
The Danish Government and Danish Regions launched the National Strategy for Personalised Medicine 2017-2020 in December 2016. The strategy creates the foundation for a balanced development of personalised medicine in Denmark for the benefit of patients - now and in the future. The National Genome Center (NGC) will serve a key role in the realisation of the strategy. In December 2018 the Novo Nordisk Foundation approved a framework grant of DKK 990 million over 4.5 years for establishing and operating the infrastructure of the National Genome Centre.
About the National Genome Center
The core mission of the NGC, is to establish and operate a state-of-the-art and secure national infrastructure for personalised medicine in cooperation with the Danish Regions and universities. The infrastructure of NGC consists of the National WGS Center and the National HPC Center, which includes the National Genome Database, National Knowledge Databases, central services and development of a National Interpretation Tool.
The Chief Bioinformatics Officer (CBO) is responsible for the coordination of bioinformatics activities within and in relation to NGC, including the national collaborations with clinical and research environments. Overall the CBO coordinates the development of bioinformatics services for use in clinical settings and for research purposes, and collaborates with the Chief Medical Officer regarding the clinical requirements. The main task of the CBO is to coordinate the development of bioinformatics specifications for the National Genome Database, the National Knowledge Databases and the National Interpretation Tool. The CBO exerts this task in close collaboration with the bioinformatics operation team of the HPC Center, where the CBO ensures that the bioinformatic analyses developed and implemented effectively supports the clinical use of the HPC Center.
The CBO will lead a team of bioinformaticians to achieve this successfully. Considering the close interlink between the bioinformatics and technical developments of the infrastructure the CBO refers to the Director General HPC.
In addition to this, the CBO is responsible for maintaining NGC’s international network within the field of bioinformatics and contributing to international collaborations.
- Technical leadership and management of all R&D staff and programs related to bioinformatics analysis and application development.
- Working with users and operations, develop specifications and development plans as a roadmap for the center.
- Development of bioinformatics specifications for the Databases, and Interpretation Tool.
- Drive, with users and management, the generation of collateral technical literature to support product launches, as well as novel applications that will help drive systems and consumable market adoption.
- As part of executive team, contribute to instrument, software product specifications and development, drawing on NGS experience.
- Work closely with operations and quality teams to effectively and efficiently transfer products from the lab to users.
Educational and Experience Requirements
The CBO will have an academic master degree and a PhD in Bioinformatics, genetics or molecular biology with a strong scientific profile and experience of bioinformatics service from a clinical setting.
Furthermore the CBO will have:
- Experience with ISO validation and accreditation in a clinical setting for genomic analysis.
- Experience in a genomics-related or bioinformatics-related field.
- Experience with ethical approval processes for human genome sequences projects such as dealing with data protection authorities and ethical board.
- Clearly recognized profile within precision medicine, clinical genome sequencing, predictive modeling, intelligent pipelines, biomedical informatics, bioinformatics.
- Detailed working knowledge of modern sequencing methods, the field of genomics, and bioinformatics.
- Detailed working knowledge of NGS bioinformatics tools used for clinical diagnostics and for research and associated data types.
- General understanding of all "wet lab" elements in and around NGS, including sample and target prep, amplification and sequencing biochemistries, polymerase enzymology, sequence analysis algorithms pipelines and standard sequencing read out formats.
- Demonstrated experience in computational analyses, computational biology, machine learning, algorithm development and testing.
- Deep expertise in efficient data structures for big data and data distribution technologies.
- Proficient in programming languages such as shell scripting, Python, R and experience with version control.
- Track record of working with HPC operations teams to develop robust processing environment on the HPC systems.
- An exemplary record of accomplishments
- Experience in managing a team of bioinformaticians.
- High degree of personal integrity, scientific rigor, strong interpersonal skills, comfortable in an interdisciplinary environment.
- High ambitions for the Danish National Genome Center
- Strong communication skills, both written and verbal. Works independently, but interactively.
- Strong organizational and record keeping skills.
- Enjoys and is effective giving scientific presentations, both internally and externally.
- Highly motivational and interactive both within his/her chain of command, but ability to interact and influence peers and CEO. High energy, but disciplined, approach to his/her departments work.
- Comfortable working in an ambitious, but resource limited environment.
As a manager you set the direction and deliver results in cooperation with the rest of the group (Koncernen). You are visionary, strategic and analytically strong, while you have a look at the quality of the individual product. In relation to employees, you work confidently and have the ability to develop them. You set staff management high and manage to exercise visible and credible leadership. Furthermore, you have good collaboration skills and achieve results through dialogue with many and strong stakeholders. You have great impact and can prioritize, make decisions and achieve the goals.
You will get staff management for approx. 6 committed employees.
Working at the Danish National Genome Center
We offer an interesting and challenging job in an international atmosphere with focus on the patient, research, innovation and clinical advice for the benefit of the surrounding community. We place emphasis on a high level of professionalism among our staff, so skills development is an integral part of our organization. We offer a great flexibility in the position.
The Danish National Genome Center is an organization under the Danish Ministry of Health and is located at Ørestads Boulevard 5, 2300 København S, together with Statens Serum Institute and the Danish Health Data Authority. The organization is expected to have a core of approx. 100 employees.
Teams of employment
Salery and terms of employment are negotiated pursuant to “the Framework Agreement on contrack appointment of government executives” (Rammeaftale om kontraktansættelse af chefer i staten) with placement in salery group 1 (salery bracket 37/lønramme 37). The position is expected to be for a fixed term of years in accordance with principles in “Agreement on employment on fixed terms” (aftale om åremålsansættelse). Employment depends on the right authorization approvals (ansættelsen afhænger af de rette bemyndigelsesgodkendelser).
It is a requirement that you can pass security clearance by the Danish authorities and maintain the security throughout your employment.
For further information about the position you are welcome to contact acting director general of the National Genome Center, Peter Løngreen (phone +45 2944 1499)
Application and recruitment process
Click “Ansøg” to send your job application with curriculum vitae and diploma / exam certificates before April 28th 2019.
First round of interviews is expected to be held during week 18/2019 and second round of interviews is expected to be held during week 19/2019.
The Ministry of Health has a non smoking policy and is a non smoking workplace.
We encourage all interested to apply for the position - regardless of age, gender, religion, disabilities or ethnicity.
Please write in your application that you've seen the job at Jobfinder.